Pro-neuropeptide Y identified as prognostic biomarker for aggressive prostate cancer
Overexpression of pro-neuropeptide Y (pro-NPY) has been identified as a prognostic biomarker for aggressive prostate cancer, according to a study published in European Urology [1].
Pro-NPY is a member of the NPY family. NPY is a secreted protein and is one of the most abundant peptides in the nervous system. NPY can be cleaved into neuropeptide Y and C-flanking peptide of NPY chain, which regulates energy usage, and it is involved in learning, memory processing, and epilepsy. NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. In addition, NPY increases the proportion of energy stored as fat.
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Reference
- Iglesias-Gato D, Wikström P, et al. The proteome of primary prostate cancer. European Urology 2015. doi: 10.1016/j.eururo.2015.10.053
Keywords: prostate cancer, prognostic biomarker, pro-neuropeptide Y (pro-NPY)
7. 2. 2016 LabMedica.com
