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TB jab could help fight cancer

Scientists have found a potential new mechanism to stimulate the body's own ability to fight cancer using Bacillus Calmette-Guerin (BCG) – the germ commonly used to inoculate against tuberculosis (TB).


The researchers, Dr Wai Liu and Professor Angus Dalgleish from St George's, University of London, say this new data suggests a mechanism by which vaccines could enhance the anti-cancer activity of currently available therapies.

However, they warn that this is an early-stage study and that there is much more research to be done before patients will benefit.

Read the whole article at ecancermedicalscience

Reference

  1. Liu, W. M., Fowler, D. W., et al. (2011). Supernatants from lymphocytes stimulated with Bacillus Calmette-Guerin can modify the antigenicity of tumours and stimulate allogeneic T-cell responses British Journal of Cancer DOI: 10.1038/bjc.2011.306

Keywords: BCG, cancer vaccine, immunotherapy, cytokines

16. 8. 2011 ecancermedicalscience


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