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Sections: Cancer research | Cancer prevention | Czech oncology | NOP On-line project

Does HPV vaccination prevent the development of cervical cancer? Are there harms associated with being vaccinated?
9. 5. 2018 Cochrane Press Release | More information...

New evidence published in the Cochrane Library [1] shows that human papilloma virus (HPV) vaccines protect against cervical lesions in young women, particularly in those who are vaccinated between the ages of 15 and 26. It also summarises findings on harms that have been assessed in randomised controlled trials.

Large study shows no evidence that vitamin D can reduce lung cancer risk
27. 4. 2018 vitamin D, lung cancer risk, observational study | More information...

A new study by the International Agency for Research on Cancer (IARC), published online in the Annals of Oncology [1], found that there was no association between circulating vitamin D levels and lung cancer risk. The report presents a robust analysis of more than 5300 case-control pairs nested within 20 international prospective cohort studies. This is the largest observational study to date on the relationship between vitamin D and cancer.

Links between red meat and distal colon cancer
2. 4. 2018 University of Leeds Press Release | More information...

A new study [1] suggests that a diet free from red meat significantly reduces the risk of a type of colon cancer in women living in the United Kingdom.

The IARC perspective on colorectal cancer screening
27. 3. 2018 IARC Press Release | More information...

Colorectal cancer is the third most common cancer in men and the second most common in women and represents almost 10% of the annual global cancer incidence. Yet the disease is preventable with a healthy lifestyle and efficient screening. The International Agency for Research on Cancer (IARC) Handbooks of Cancer Prevention programme has evaluated the effectiveness of various colorectal cancer screening methods.

Major study shows prostate MRI reveals more cancers which need treatment and reduces overdiagnosis compared to standard biopsy
19. 3. 2018 European Association of Urology Press Release | More information...

A large international study has shown that an MRI scan can reduce the number of invasive prostate biopsies by up to 28%. The PRECISION [1] trial shows that using MRI to target prostate biopsies leads to more of the harmful prostate cancers, and fewer harmless cancers being diagnosed. Given that more than a million men in Europe undergo a prostate biopsy every year, the authors believe that this work could change clinical practice. The results are presented at the European Association of Urology Congress in Copenhagen, with simultaneous publication in The New England Journal of Medicine [2].

One-off PSA screening for prostate cancer does not save lives
6. 3. 2018 Cancer Research UK Press Release | More information...

Inviting men with no symptoms to a one-off PSA test for prostate cancer does not save lives according to results from the largest ever prostate cancer trial conducted over 10 years by Cancer Research UK-funded scientists and published today (Tuesday) in the Journal of the American Medical Association (JAMA) [1].

Colorectal cancer: Combined analysis enhances risk prediction
27. 2. 2018 DKFZ Press Release | More information...

If first-degree relatives are affected by colorectal cancer, this indicates a person’s own elevated risk of developing bowel cancer. The same holds true for people who have large numbers of genetic risk markers in their genome. Both factors are usually used alternatively, not combined, to predict risk. Scientists from the German Cancer Research Center (DKFZ) in Heidelberg have now shown that a combination of family history and an analysis of genetic markers helps determine a person’s colorectal cancer risk more precisely.

New international project for innovation of cancer care in Europe
8. 2. 2018 | More information...

Improvement and innovation of cancer care and its availability to all citizens belongs to EU priorities in the area of public health. The INTENT project is one of the new contributions in this field, aiming to find solutions for innovative patient-centred cancer care.

CancerSEEK: Generalised screening for multiple cancer types
18. 1. 2018 EurekAlert Press Release | More information...

Researchers have developed a blood test based on combined analysis of DNA and proteins that may allow earlier detection of eight common cancer types. The findings have just been published in the journal Science [1].

Evidence mounts of link between severe gum disease and various cancers
17. 1. 2018 ecancer.org | More information...

Three recent studies have added further weight to the link between periodontitis and overall cancer risk. The first [1] showed that severe periodontitis was associated with a 24 percent increased risk. The second [2] and third [3] investigated the role of bacteria causing periodontitis in the development of oral cancers and certain other cancers.

Cancer in the older population of the Czech Republic
27. 10. 2015 IBA MU | More information...

Population ageing has become a challenge to cancer care in developed countries. Particularities of the older population must be taken into account when considering cancer treatment. However, there is a lack of consensus on guidelines for this population due to the underrepresentation of older patients in clinical trials.

Balance between the centralisation and availability of cancer care: Institute of Biostatistics and Analyses develops the European model of a Comprehensive Cancer Care Network
4. 5. 2015 IBA MU | More information...

The Czech Republic has become a key player in European activities focusing on the development and assessment of cancer care; the Cancer Control Joint Action (CanCon) undoubtedly belongs to the most prestigious ones. Based on the Czech information system of cancer care, the Czech Republic has been selected as a model country for the development of a Comprehensive Cancer Care Network (CCCN). This part of the CanCon project is coordinated by Prof Lucio Luzzatto from the Tumour Institute of Tuscany (Istituto Toscano Tumori, ITT), who paid a visit to Brno on 24 April 2015 not only to learn about the Czech results up to now, but also about cancer research and healthcare provided to cancer patients in the Czech Republic in general, and in the South Moravian Region in particular.

Results of personalised invitations of Czech citizens to cancer screening programmes in 2014
16. 4. 2015 Czech Ministry of Health, Institute of Biostatistics and Analyses of Masaryk University | More information...

The project of personalised invitations of citizens to cancer screening programmes was launched in the Czech Republic in January 2014. Women are invited to participate in breast cancer screening and cervical cancer screening; men and women are invited to participate in colorectal cancer screening. The project aims to enhance the current cancer prevention programmes, and to increase their participation rates; therefore, personalised invitations are sent to citizens who do not participate in cancer screening programmes in the long term, and thus are at a higher risk of developing cancer.

Cancer screening programmes and their informational support: situation in the Czech Republic in 2014
18. 12. 2014 IBA MU | More information...

A special issue of Klinicka onkologie (the official journal of the Czech Society for Oncology), published in December 2014, is dedicated to the assessment of cancer prevention efforts and results in the Czech Republic. A team of authors not only described the current situation in cancer prevention programmes in the Czech Republic, but also pointed out weak spots in cancer prevention efforts.

Another international study confirmed longer survival of Czech cancer patients
5. 12. 2014 IBA MU | More information...

Over the last 15 years, the Czech Republic has been closing the gap on Western Europe in terms of 5-year survival rates in selected cancer types, and nowadays is significantly beyond the average of other post-communist countries. The latest results from the international study CONCORD-2 have again confirmed this trend.

Cancers in 2012 due to overweight and obesity: the Czech Republic has the highest proportion in Europe
26. 11. 2014 International Agency for Research on Cancer (IARC), Institute of Biostatistics and Analyses (IBA MU) | More information...

A new study by the International Agency for Research on Cancer (IARC), the specialised cancer agency of the World Health Organization (WHO), shows that nearly half a million new cancer cases per year can be attributed to high body mass index (BMI).

Czech Cancer Care in Numbers: a brief summary
8. 10. 2014 IBA MU | More information...

A compact description of cancer care in the Czech Republic was presented at the ESMO 2014 Congress in Madrid, Spain. The Czech Society for Oncology and the Institute of Biostatistics and Analyses of the Masaryk University worked together to highlight the alarmingly growing cancer burden of the Czech population, to explain the current National Cancer Control Programme and ongoing cancer screening programmes, and to comment the latest survival rates of Czech cancer patients.

Cancer burden in the Czech Republic: European and worldwide comparison
10. 9. 2014 IBA MU | More information...

The global cancer burden is on the rise, warned IARC at the beginning of 2014. The Czech Republic is no exception: cancer incidence rates are growing in our country, too. But where does the Czech Republic rank among other European countries (or even globally) in terms of cancer burden?

Survival rates of Czech cancer patients have improved
13. 4. 2014 IBA MU | More information...

Earlier this year, two studies analysing survival rates of cancer patients in the Czech Republic and across Europe were published [12]. Survival rates of cancer patients belong to key parameters in terms of evaluation of cancer care outcomes, and of fulfilling the National Cancer Control Programme. The good news from both studies is that outcomes of the Czech cancer care have improved in most diagnoses: both in terms of time trends, and when compared to other European countries. However, there is much space for improvements in cancer prevention efforts as well as early diagnosis of less advanced stages; and last but not least, the availability of cancer diagnosis and treatment in individual regions of the Czech Republic needs to be further improved.

Tobacco consumption in the Czech Republic ranks among the highest globally, while anti-smoking measures are among the poorest worldwide
2. 4. 2014 IBA MU | More information...

Smoking is one of the most important known risk factors for cancer. Most European countries are well aware of this fact, and have adopted various measures aimed at decreasing the number of smokers among the population, which should not only improve the population’s state of health, but also save costs for treatment of smoking-related diseases. Unfortunately, international studies and comparisons have shown that the Czech Republic is miles apart from those countries.

Personalised invitations of Czech citizens to cancer screening programmes
15. 1. 2014 IBA MU | More information...

In January 2014, a project of personalised invitations for cancer screening programmes was launched in the Czech Republic. In particular, citizens are invited to participate in colorectal cancer screening (men and women), as well as breast cancer screening and cervical cancer screening (women). Personalised invitations are aimed at citizens who have not participated in cancer screening programmes in the long term, and therefore are at a higher risk of developing cancer. The project is expected to increase participation rates in Czech cancer screening programmes.

OECD Health at a Glance 2013: Czech breast cancer screening programme led to an improvement of survival rates in breast cancer patients
28. 11. 2013 IBA MU | More information...

Health at a Glance is published by OECD every two years, providing the assessment and comparison of health care in individual member countries based on clearly defined indicators. In the area of cancer care, Health at a Glance primarily focuses on three diagnoses which can be detected at early stages, and for which organised screening programmes are widely recommended: colorectal cancer, breast cancer, and cervical cancer.

New OECD publication evaluates cancer care and survival of cancer patients
21. 11. 2013 IBA MU | More information...

On 30 October 2013, OECD published “Cancer Care” [1] as a summary of indicators for care provided to cancer patients in participating countries. According to the attached “country note” for the Czech Republic [2], cancer outcomes could be further improved, despite recent improvements in survival rates of cancer patients. Estimated 5-year survival rates for selected cancers are lower than the OECD average, and mortality rates are generally high, as a result of high cancer incidence rates among the Czech population, and a relatively late diagnosis.

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